RH5624 Hydroxypropyl-β-Cyclodextrin | CAS 94035-02-6 | USP Grade >99%

Product Overview

RH5624 Hydroxypropyl-β-Cyclodextrin (HP-β-CD), CAS 94035-02-6, is a high-purity modified β-cyclodextrin supplied as USP Grade with purity >99%.

Hydroxypropyl-β-Cyclodextrin is a hydroxypropyl-substituted derivative of β-cyclodextrin. It retains the characteristic cyclodextrin cavity while offering improved aqueous solubility compared with unmodified β-cyclodextrin.

These properties make HP-β-CD useful for inclusion complex research, solubility studies, formulation development, host-guest chemistry and biochemical research.

Key Features

• USP Grade

• Purity >99%

• CAS 94035-02-6

• Hydroxypropyl-modified β-cyclodextrin

• Commonly abbreviated as HP-β-CD

• High aqueous solubility

• Suitable for inclusion complex research

• Suitable for solubility studies

• Suitable for formulation research

• Suitable for biochemical research

• 50 g standard packaging

Technical Specifications

Applications

• Inclusion Complex Research

• Solubility Studies

• Host-Guest Chemistry

• Molecular Encapsulation Research

• Formulation Research

• Cyclodextrin Research

• Biochemical Research

• Pharmaceutical Research

• Physicochemical Research

• Life Science Research

Hydroxypropyl-β-Cyclodextrin for Solubility Studies

Hydroxypropyl-β-Cyclodextrin is widely investigated as a modified cyclodextrin for improving the apparent aqueous solubility of suitable compounds.

Its hydrophobic internal cavity can interact with compatible guest molecules, while the hydrophilic exterior supports aqueous compatibility.

Researchers can use HP-β-CD to study inclusion complex formation, dissolution behavior and solubility-related properties of suitable compounds.

Hydroxypropyl-β-Cyclodextrin for Inclusion Complex Research

The cyclodextrin cavity of HP-β-CD enables non-covalent interactions with suitable guest molecules.

Depending on molecular size, structure and experimental conditions, a guest molecule may interact with the internal cavity to form an inclusion complex.

This makes Hydroxypropyl-β-Cyclodextrin useful in host-guest chemistry, molecular recognition and encapsulation-related research.

Hydroxypropyl-β-Cyclodextrin for Formulation Research

HP-β-CD is commonly investigated in formulation research involving compounds with limited aqueous solubility.

Complex formation with Hydroxypropyl-β-Cyclodextrin may modify properties such as apparent solubility, dissolution behavior and stability of suitable guest compounds.

The optimal HP-β-CD concentration and formulation conditions depend on the properties of the target molecule and the experimental system.

Hydroxypropyl-β-Cyclodextrin vs β-Cyclodextrin

Hydroxypropyl-β-Cyclodextrin is derived from β-cyclodextrin through hydroxypropyl substitution.

Both materials retain the characteristic β-cyclodextrin cavity, but hydroxypropyl substitution generally provides substantially improved aqueous solubility.

This makes HP-β-CD particularly useful when the limited water solubility of unmodified β-cyclodextrin is undesirable for a particular research application.

Hydroxyethyl-β-Cyclodextrin vs Hydroxypropyl-β-Cyclodextrin

Both products are hydrophilic derivatives of β-cyclodextrin, but their substituent groups are different:

• Hydroxyethyl-β-Cyclodextrin: hydroxyethyl modification

• Hydroxypropyl-β-Cyclodextrin: hydroxypropyl modification

These structural differences can influence aqueous properties, substitution characteristics and interactions with guest molecules.

The appropriate derivative should therefore be selected according to the specific experimental application.

Other Modified β-Cyclodextrins

Other modified β-cyclodextrins available in this series include:

• Glucosyl-β-Cyclodextrin

• Hydroxyethyl-β-Cyclodextrin

• Sulfobutyl-β-Cyclodextrin

• Methyl-β-Cyclodextrin

These derivatives provide different physicochemical characteristics for inclusion complex, solubility and formulation research.

Product Advantages

RH5624 Hydroxypropyl-β-Cyclodextrin is supplied as USP Grade with purity >99%.

Its high purity, hydrophilic modification and characteristic cyclodextrin cavity make it suitable for a wide range of biochemical, formulation and inclusion complex research applications.

The standard package is 50 g.

Storage and Handling

• Keep the container tightly sealed.

• Protect from moisture and contamination.

• Store according to the recommended product conditions.

• Follow appropriate laboratory handling procedures.

• Refer to the applicable SDS for detailed storage and handling information.

Packaging

Standard Packaging: 50 g

Other quantities can be discussed upon request.

Frequently Asked Questions (FAQ)

What is RH5624 Hydroxypropyl-β-Cyclodextrin?

RH5624 Hydroxypropyl-β-Cyclodextrin, CAS 94035-02-6, is a hydroxypropyl-modified β-cyclodextrin supplied as USP Grade with purity >99%.

What is HP-β-CD?

HP-β-CD is the commonly used abbreviation for Hydroxypropyl-β-Cyclodextrin.

What is Hydroxypropyl-β-Cyclodextrin used for?

It is used in solubility studies, inclusion complex research, host-guest chemistry, formulation development, molecular encapsulation and biochemical research.

Is Hydroxypropyl-β-Cyclodextrin water soluble?

Hydroxypropyl modification provides substantially improved aqueous solubility compared with unmodified β-cyclodextrin, making HP-β-CD useful for aqueous research systems.

What is the difference between β-Cyclodextrin and Hydroxypropyl-β-Cyclodextrin?

HP-β-CD is a hydroxypropyl-modified derivative of β-cyclodextrin. The modification improves aqueous solubility while retaining the characteristic cyclodextrin cavity.

What is the CAS number of Hydroxypropyl-β-Cyclodextrin?

The CAS number listed for RH5624 Hydroxypropyl-β-Cyclodextrin is 94035-02-6.

What is the purity of RH5624?

RH5624 is supplied as USP Grade with purity >99%.

What packaging is available?

The standard package for RH5624 Hydroxypropyl-β-Cyclodextrin is 50 g.