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Home Biological Reagents RH0028 Tris Hydrochloride (Tris-HCl, Tris(hydroxymethyl)aminomethane Hydrochloride)
RH0028 Tris Hydrochloride (Tris-HCl, Tris(hydroxymethyl)aminomethane Hydrochloride)
RH0028 Tris Hydrochloride (Tris-HCl, Tris(hydroxymethyl)aminomethane Hydrochloride)
RH0028 Tris Hydrochloride (Tris-HCl) is a high-purity biological buffer widely used in molecular biology, protein purification, electrophoresis, nucleic acid extraction, enzyme assays and biochemical research. It provides excellent buffering capacity in the neutral to alkaline pH range.
  • RH0028

  • 500 g / 1 kg

  • Pharmaceutical Grade

  • C4H12ClNO3

  • 157.60 g/mol

  • 7.0–9.0 (pKa 8.06 at 25°C)

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Product Overview

Tris Hydrochloride (Tris-HCl) is the hydrochloride salt form of Tris(hydroxymethyl)aminomethane (TRIS) and is one of the most widely used biological buffers in life science research. It provides excellent buffering capacity in the neutral to slightly alkaline pH range while exhibiting high water solubility, low biological interference and outstanding chemical stability.

Unlike TRIS free base, Tris Hydrochloride can be used directly for preparing Tris-HCl buffer systems with minimal pH adjustment. It is extensively used in molecular biology, protein purification, nucleic acid extraction, electrophoresis, cell culture, enzyme assays and diagnostic reagent development.

Key Features

  • High purity pharmaceutical grade

  • Ready-to-use hydrochloride salt

  • Excellent buffering capacity

  • Stable neutral to alkaline pH

  • Highly water soluble

  • Low biological interference

  • Excellent chemical stability

  • Suitable for molecular biology

  • Reliable batch-to-batch consistency

  • Widely used in life science research

Technical Specifications

Parameter

Specification

Product Code

RH0028

Product Name

Tris Hydrochloride

Chemical Name

Tris(hydroxymethyl)aminomethane Hydrochloride

CAS No.

1185-53-1

Molecular Formula

C4H12ClNO3

Molecular Weight

157.60 g/mol

Purity

Pharmaceutical Grade

Effective Buffer Range

pH 7.0–9.0

Appearance

White Crystalline Powder

Solubility

Freely Soluble in Water

Package

500 g / 1 kg

Applications

  • Molecular Biology

  • DNA & RNA Extraction

  • Protein Purification

  • Cell Culture

  • PCR Experiments

  • Agarose Gel Electrophoresis

  • SDS-PAGE Electrophoresis

  • Enzyme Assays

  • Laboratory Buffer Preparation

  • Diagnostic Reagent Development

Product Advantages

RH0028 Tris Hydrochloride provides excellent buffering performance and allows rapid preparation of Tris-HCl buffer systems with minimal pH adjustment. It is one of the most commonly used buffering reagents in molecular biology, protein chemistry and biotechnology laboratories.

Manufactured under strict quality standards, SANYU GROUP Tris Hydrochloride offers high purity, excellent consistency and reliable performance for universities, research institutes, biotechnology companies and pharmaceutical manufacturers worldwide.

Storage and Handling

  • Store in a cool, dry and well-ventilated place.

  • Keep the container tightly closed after use.

  • Protect from moisture and direct sunlight.

  • Store at room temperature.

  • Avoid contamination during handling.

Packaging

Standard packaging:

  • 500 g

  • 1 kg

OEM packaging and bulk quantities are available upon request.

Frequently Asked Questions (FAQ)

What is Tris Hydrochloride used for?

Tris Hydrochloride is widely used in molecular biology, protein purification, DNA and RNA extraction, electrophoresis, enzyme assays and laboratory buffer preparation.

What is the difference between TRIS and Tris Hydrochloride?

TRIS is the free base form, while Tris Hydrochloride (Tris-HCl) is the hydrochloride salt form. Tris Hydrochloride dissolves readily in water and is commonly used for preparing Tris-HCl buffer solutions with less pH adjustment.

What is the effective pH range of Tris Hydrochloride?

Tris Hydrochloride is commonly used for buffer systems operating in the pH range of 7.0–9.0, making it suitable for most molecular biology and biochemical applications.

How should Tris Hydrochloride be stored?

Store the product in a cool, dry place away from moisture and direct sunlight. Keep the container tightly sealed after opening.

Do you provide OEM packaging?

Yes. SANYU GROUP provides OEM labeling, customized packaging and bulk supply services for distributors, research laboratories, biotechnology companies and pharmaceutical manufacturers.

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