Microspheres for IVD & POCT Assay Development
Colored, fluorescent, time-resolved fluorescent and functionalized microspheres for lateral flow, immunodiagnostics, flow cytometry and point-of-care testing.
Fluorescent Microspheres
High-brightness internally dyed microspheres for sensitive and quantitative detection.
Time-Resolved Fluorescent Microspheres
Long fluorescence lifetime and reduced background interference for high-sensitivity assays.
Streptavidin & Functional Microspheres
Streptavidin, carboxyl, amino, epoxy and custom surface options for biomolecule coupling.
Flow Cytometry & Specialty Microspheres
Consistent particle concentration and fluorescence options for calibration and quantitative analysis.
Bring the assay context. Narrow the particle starting point.
We offer a diverse range of precision-engineered solutions, from advanced chromatography media to magnetic beads and fluorescent microspheres, empowering industries worldwide.
| Assay Platform | Recommended Microsphere | Detection Mode | Surface | Main Benefit |
| Visual LFIA | Colored Carboxyl Microspheres | Visual | COOH | Strong test-line contrast |
| Quantitative LFIA | Fluorescent Microspheres | Fluorescence reader | COOH / SA | Higher sensitivity |
| High-Sensitivity LFIA | Time-Resolved Fluorescent Microspheres | TRF reader | COOH | Low background signal |
| LTIA | White Carboxyl PS Microspheres | Turbidimetry | COOH | Strong light scattering |
| Latex Agglutination | Plain or Colored Microspheres | Visual / agglutination | Plain / COOH | Rapid qualitative detection |
| Flow Cytometry | Fluorescent or Counting Microspheres | Flow cytometer | Plain / functional | Calibration and quantification |
| Biotin-Based Assays | Streptavidin Microspheres | Optical / fluorescent | Streptavidin | High-affinity biotin capture |
| Assay Platform | Recommended Microsphere | Detection Mode | Surface | Main Benefit |
DEFINE THE PARAMETERS
Custom Microspheres for Your Diagnostic Assay
SHBC provides microsphere solutions for IVD and POCT assay development, with support for product selection, customization, evaluation and scale-up supply.
Custom Microspheres for Your Diagnostic Assay
Configure the material around your platform, from early screening to repeatable production. Availability is confirmed against the actual project requirement.
Particle Material
Polystyrene, PMMA and verified custom polymers
Particle Size
Nanometer-to-micrometer options within actual production capability
Color
Red, blue, black and verified custom visible colors
Fluorescence
Available excitation/emission channels and spectrum data
Surface Chemistry
Plain, carboxyl, amino, streptavidin and verified custom groups
Solid Content
Standard or customized concentration
Buffer
Standard or customer-specified buffer where feasible
Packaging
R&D samples, pilot quantities and bulk supply
Conjugation Support
Support for antibody, antigen, protein and other biomolecule conjugation workflows
OUR ADVANTAGES
Why IVD Developers Choose SHBC
Quality information for development and transfer
Download Product Catalogue
FREQUENTLY ASKED QUESTIONS
Microspheres For IVD & POCT Frequently Asked Questions
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What types of microspheres are available for IVD and POCT assays?
SHBC offers colored microspheres, fluorescent microspheres, time-resolved fluorescent microspheres, carboxyl polystyrene microspheres, streptavidin microspheres and specialty counting microspheres for different IVD and POCT platforms.
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Which microspheres are recommended for lateral flow assays?
Colored carboxyl microspheres are suitable for visual detection, while fluorescent and time-resolved fluorescent microspheres are suitable for reader-based and higher-sensitivity assays.
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What is the difference between colored and fluorescent microspheres?
Colored microspheres provide a visible optical signal for qualitative or semi-quantitative detection, while fluorescent microspheres require a compatible fluorescence reader and are more suitable for quantitative or higher-sensitivity detection.
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Can the particle size and surface carboxyl density be customized?
Yes. Particle size, solid content, surface functionality, carboxyl level, color and packaging can be customized depending on project requirements and production feasibility.
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Which microspheres are suitable for EDC/NHS antibody coupling?
Carboxyl-functionalized microspheres are suitable for EDC/NHS activation and covalent coupling with amine-containing biomolecules such as antibodies and proteins.
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Do you provide streptavidin-coated microspheres?
Yes. Streptavidin-functionalized microspheres are available for biotin-based capture and assay development.
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Can you recommend microspheres based on our fluorescence reader?
Yes. Please provide the excitation and emission channels of your reader, and our technical team can recommend compatible fluorescent microsphere options.
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Do you provide samples for assay evaluation?
Yes. Evaluation samples may be available depending on the product type and specification. Please contact us with your target application and required size.
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What documentation is available with each batch?
Available documentation may include COA, SDS, particle size data, solid content, surface information and fluorescence spectrum data, depending on the product type.
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Can you support pilot production and commercial-scale supply?
Yes. SHBC supports R&D evaluation, pilot-scale supply, OEM/ODM and bulk production for qualified projects.