This bar serves to notify visitors of important updates

CARBOXYL MAGNETIC BEADS SUPPLIER

SHBC Carboxyl Magnetic Beads

High-Performance Magnetic Beads for Chemiluminescence, Bioseparation & Molecular Diagnostics

Carboxyl Magnetic Beads

PRODUCT CENTER

Carboxyl Magnetic Beads Products

Carboxyl Magnetic Beads

BRIEF INTRODUCTION

What are Carboxyl Magnetic Beads?

SHBC Carboxyl Magnetic Beads are high-performance sandwich-structured magnetic microspheres specifically developed for chemiluminescent immunoassays (CLIA), molecular diagnostics, immunoprecipitation, cell separation, protein immobilization, and nucleic acid capture.
The unique sandwich architecture consists of a porous polymer core, a magnetic layer, and a specially engineered polymer shell. This advanced design provides excellent buoyancy, highly uniform particle size, rapid magnetic response, and low non-specific adsorption, significantly improving assay sensitivity while reducing background signals.
The bead surface is densely functionalized with carboxyl (-COOH) groups, allowing efficient covalent coupling with biomolecules containing primary amino groups, including antibodies, proteins, peptides, enzymes, oligonucleotides, and nucleic acids through stable amide bond formation.
Designed for research laboratories, biotechnology companies, diagnostic reagent manufacturers, and pharmaceutical developers, SHBC Carboxyl Magnetic Beads deliver reliable performance from R&D to commercial production.

KEY BENIFITS

Advantages of Carboxyl Magnetic Beads

Unique Sandwich Structure

Unlike conventional solid magnetic particles, SHBC magnetic beads feature a three-layer sandwich structure:

Porous polymer core

High-performance magnetic layer

Functional polymer coating

This structure combines strong magnetic responsiveness with excellent suspension stability while maintaining an extremely uniform particle size distribution.

Rich Carboxyl Functional Groups

The bead surface contains abundant carboxyl groups (-COOH), enabling efficient EDC/NHS activation for covalent immobilization of:

Antibodies

Proteins

Peptides

Enzymes

DNA

RNA

Oligonucleotides

 Amino-modified biomolecules

The resulting amide bonds provide excellent long-term stability for diagnostic and bioseparation applications.

Product-Features

Low Non-Specific Binding

The specially engineered polymer coating significantly reduces non-specific adsorption.

Benefits include:

Lower background signal

Higher signal-to-noise ratio

Improved assay sensitivity

Better reproducibility

Higher diagnostic accuracy

Fast Magnetic Response

The optimized magnetic layer provides:

Rapid magnetic separation

Excellent recovery efficiency

Short washing time

Improved automation compatibility

High-throughput processing capability

Highly Uniform Particle Size

Precise manufacturing technology ensures:

Narrow particle size distribution

Excellent batch consistency

Stable suspension

Repeatable assay performance

Reliable experimental results

PRODUCT ADVANTAGES

Technical Advantages of Carboxyl Magnetic Beads

FeatureBenefits
Sandwich StructureImproved buoyancy and suspension stability
High Magnetic ContentRapid magnetic response
Rich Carboxyl GroupsHigh coupling efficiency
Polymer SurfaceLow non-specific adsorption
Uniform Particle SizeExcellent reproducibility
Stable ChemistryLong-term storage stability
Multiple Particle SizesSuitable for different applications
OEM & ODM SupportCustom development available
Working Principle

PRODUCT ADVANTAGES

Working Principle of Carboxyl Magnetic Beads

SHBC Carboxyl Magnetic Beads utilize surface carboxyl groups for biomolecule immobilization.
The carboxyl groups are activated using EDC/NHS chemistry and react with primary amino groups on biomolecules to form stable amide bonds.
This stable covalent linkage enables:

Antibody immobilization

DNA probe immobilization

Protein coupling

RNA capture

Peptide conjugation

Enzyme immobilization

The magnetic core allows rapid magnetic separation while maintaining biological activity.

INDUSTRIES WE SERVED

Typical Applications of Carboxyl Magnetic Beads

CLIA

Chemiluminescent Immunoassay (CLIA)

Ideal for automated chemiluminescent diagnostic platforms.Applications include:
Infectious disease testing
Tumor marker detection
Hormone assays
Cardiac marker testing
Autoimmune diagnostics
Immuno precipitation (IP)

Immuno precipitation (IP)

Efficient enrichment and purification of target proteins.
Suitable for:
Protein interaction studies
Protein complex isolation
Western blot sample preparation
Cell Separation

Cell Separation

Fast magnetic isolation of:
Immune cells
Stem cells
Tumor cells
Primary cells
Rare cell populations
Nucleic Acid Capture

Nucleic Acid Capture

Excellent platform for:
DNA purification
RNA purification
PCR sample preparation
Next-generation sequencing
Molecular diagnostics
Gene analysis
Protein Purification

Protein Purification

Efficient immobilization and purification of:
Recombinant proteins
Antibodies
Enzymes
Antigens
Biomolecule Coupling

Biomolecule Coupling

Suitable for conjugation of:
Antibodies
Proteins
Peptides
Enzymes
Aptamers
Oligonucleotides

REASONS WHY CHOOSE

Why Choose SHBC Carboxyl Magnetic Beads?

Advanced sandwich structure technology
High magnetic responsiveness
Rich surface carboxyl groups
Low non-specific adsorption
Excellent suspension stability
Uniform particle size distribution
High coupling efficiency
Superior batch-to-batch consistency
Compatible with automated CLIA systems
OEM & ODM customization supported
Carboxyl Magnetic Beads1
Carboxyl Magnetic Beads4

CUSTOMIZATION

Quality Assurance

SHBC maintains strict quality control throughout production to ensure:
Consistent particle size
Stable magnetic performance
High coupling efficiency
Excellent reproducibility
Reliable batch consistency
Long-term storage stability
Each production batch undergoes comprehensive quality testing before shipment.

REASONS WHY CHOOSE

Customization Services

SHBC offers flexible OEM & ODM services, including:
Customized particle sizes
Customized concentrations
Surface functionalization
Special packaging
Bulk production
Technical support
Coupling optimization Application development
Carboxyl Magnetic Beads2
Carboxyl Magnetic Beads3

CUSTOMIZATION

Industries We Serve

We support complete customization including:

Biotechnology Companies IVD Manufacturers Pharmaceutical Companies

CRO & CDMO Organizations Universities Research Institutes Clinical Laboratories Molecular Diagnostic Developers Life Science Distributors

PRODUCT SPECIFICATIONS

Available specifications of Carboxyl Magnetic Beads

ParameterAvailable Options
Particle Size0.1μm 0.2um 0.5um,1 μm 1.5μm2μm2.8 μm,3μm5μm10μm15μm20μm30μm40μm50μm100μm
Surface GroupCarboxyl (-COOH)
Magnetic ResponseHigh
SuspensionStable
Coupling ChemistryEDC/NHS
Storage2–8°C
OEM ServiceAvailable

Contact SHBC

Shanghai SanYu Biotechnology Co.,Ltd td.
Your Reliable Partner for Magnetic Bead Solutions

Advanced Manufacturing Technology

Strict Quality Control

Stable Supply Chain

OEM & ODM Service

Professional Technical Support

Fast Global Delivery

Competitive Pricing

Customized Solutions for Your Applications

ADVANATGES

Looking for a reliable Carboxyl Magnetic Beads supplier?

Partner with a trusted manufacturer of high-quality Carboxyl Magnetic Beads for diagnostic, research, and industrial applications. Whether you need standard products or application-specific solutions, our team is ready to help you find the right microspheres for your project.

FREQUENTLT ASKED QUESTIONS

FAQs of Carboxyl Magnetic Beads

  • What are Carboxyl Magnetic Beads and why are they widely used in chemiluminescence immunoassays and molecular diagnostics?

    Created with Sketch.
    形状 Created with Sketch.

    SHBC Carboxyl Magnetic Beads feature a unique sandwich structure with a porous polymer core, magnetic layer, and functional outer coating. Their abundant carboxyl groups enable stable covalent coupling with proteins, antibodies, peptides, and nucleic acids. The beads provide low non-specific adsorption, high sensitivity, rapid magnetic separation, and excellent batch consistency, making them ideal for chemiluminescent immunoassays, molecular diagnostics, and automated detection platforms.

  • What advantages does the sandwich structure of SHBC Carboxyl Magnetic Beads provide compared with conventional magnetic beads?

    Created with Sketch.
    形状 Created with Sketch.

    The sandwich structure separates the magnetic material from the functional surface. This design improves buoyancy, ensures highly uniform particle size, minimizes non-specific adsorption, and allows flexible surface modification. As a result, assays achieve lower background signals, higher sensitivity, and better reproducibility than many conventional solid magnetic beads.

  • Can your Carboxyl Magnetic Beads be used for antibody immobilization and protein coupling applications?

    Created with Sketch.
    形状 Created with Sketch.

    Yes. The abundant carboxyl groups can be activated using EDC/NHS chemistry to form stable amide bonds with primary amine-containing biomolecules such as antibodies, proteins, enzymes, peptides, and antigens. This provides efficient immobilization with high coupling efficiency and long-term stability for immunoassays and bioseparation.

  • What particle sizes and specifications are available for SHBC Carboxyl Magnetic Beads?

    Created with Sketch.
    形状 Created with Sketch.

    SHBC provides multiple particle sizes including 0.5 μm, 1 μm, 2.8 μm and 5 μm. Different concentrations, surface functionalization options, and packaging volumes are available. Custom specifications can also be developed according to assay platforms and customer requirements.

  • Are SHBC Carboxyl Magnetic Beads suitable for automated chemiluminescence analyzers and high-throughput systems?

    Created with Sketch.
    形状 Created with Sketch.

    Yes. The beads exhibit rapid magnetic response, excellent suspension stability, and narrow particle size distribution. These properties support consistent performance in automated chemiluminescence analyzers and high-throughput laboratory workflows while improving assay precision and processing efficiency.

  • Can these magnetic beads be used for nucleic acid capture, DNA/RNA purification, and molecular biology research?

    Created with Sketch.
    形状 Created with Sketch.

    Yes. After appropriate surface coupling or probe immobilization, SHBC Carboxyl Magnetic Beads are widely used for nucleic acid capture, DNA/RNA purification, molecular diagnostics, sequencing sample preparation, and other molecular biology applications requiring efficient magnetic separation.

  • How do SHBC Carboxyl Magnetic Beads help reduce background signals and improve assay sensitivity?

    Created with Sketch.
    形状 Created with Sketch.

    The specially engineered surface coating minimizes non-specific adsorption while maintaining high coupling capacity. Combined with highly uniform particle size and stable magnetic response, this significantly reduces background noise and improves assay sensitivity, reproducibility, and signal consistency.

  • What applications are most commonly supported by SHBC Carboxyl Magnetic Beads in biotechnology and IVD industries?

    Created with Sketch.
    形状 Created with Sketch.

    Typical applications include chemiluminescent immunoassays, immunoprecipitation, cell separation, protein purification, antibody immobilization, nucleic acid capture, molecular diagnostics, biosensors, and magnetic bioseparation. The beads are suitable for both research and commercial diagnostic reagent development.

  • Do you provide OEM, custom surface modification, or technical support for diagnostic reagent manufacturers?

    Created with Sketch.
    形状 Created with Sketch.

    Yes. SHBC offers OEM and ODM services, customized particle sizes, concentrations, packaging, and surface functionalization. Our technical team also supports customers with coupling optimization, application development, and scale-up production for diagnostic reagent manufacturing.

  • Why should biotechnology companies choose SHBC as their Carboxyl Magnetic Bead supplier?

    Created with Sketch.
    形状 Created with Sketch.

    SHBC combines advanced manufacturing technology with strict quality control to deliver highly uniform magnetic beads with excellent reproducibility. We provide flexible customization, reliable supply capacity, responsive technical support, and cost-effective solutions for biotechnology companies, diagnostic manufacturers, and research institutions worldwide.