Products
SHBC provides colored microspheres, fluorescent microspheres, magnetic beads, silica microspheres, chromatography packing microspheres and biological reagents for diagnostic assay development, nucleic acid extraction, protein purification and separation applications.
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PS/DVB200UM-300A
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SHBC
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200µm
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5g 10g 50g 100g 1000g
200µm Porous PS/DVB Microspheres with 300Å Pores
SHBC PS/DVB200UM-300A is a porous crosslinked polystyrene-divinylbenzene microsphere with a nominal particle size of 200µm and a pore size of 300Å.
The large spherical particles, hydrophobic polymer surface and accessible porous structure make this product suitable for adsorption, low-pressure column separation, functional carrier development and industrial purification research.
Product Overview
PS/DVB200UM-300A is manufactured from polystyrene crosslinked with divinylbenzene.
The crosslinked polymer network improves particle rigidity and dimensional stability. Its 300Å pores provide internal surface access, while the 200µm particle size supports convenient recovery, column packing and process handling.
The product can be used as a non-functionalized adsorbent or as a base matrix for further surface modification.
Key Features and Benefits
Nominal particle size of 200µm
Controlled pore size of 300Å
Porous PS/DVB polymer matrix
Crosslinked spherical structure
Hydrophobic adsorption surface
Accessible internal pore network
Convenient particle recovery
Suitable for low-pressure columns
Suitable for batch adsorption
Good process handling performance
Surface functionalization available
Custom and bulk supply supported
Product Specifications
Parameter | Specification |
|---|---|
Product Name | Porous Crosslinked PS/DVB Microspheres |
Catalog Number | PS/DVB200UM-300A |
Brand | SHBC |
Particle Size | 200µm |
Pore Size | 300Å |
Equivalent Pore Diameter | 30nm |
Matrix | Polystyrene/Divinylbenzene |
Structure | Porous and crosslinked |
Standard Surface | Hydrophobic, non-functionalized |
Main Use | Adsorption, separation and carrier development |
Manufacturer | Shanghai SanYu Biotechnology Co., Ltd. |
Pore volume, specific surface area, particle-size distribution, crosslinking degree and supply form should be confirmed in the SHBC technical data sheet.
Benefits of 200µm Particles and 300Å Pores
Convenient Process Handling
The 200µm particle size allows easier filtration, sedimentation, washing and recovery than smaller chromatography particles.
Lower Flow Resistance
Larger particles can support lower pressure drop in gravity-flow and low-pressure packed-bed systems.
Accessible Internal Surface
The 300Å pore structure provides internal space for analyte diffusion and adsorption.
Suitable for Larger Molecules
Compared with smaller-pore materials, 300Å pores can provide improved access for relatively large organic molecules and selected biomolecules.
Stable Crosslinked Structure
DVB crosslinking helps the microspheres maintain their shape during mixing, washing and repeated process cycles.
Recommended Applications
Hydrophobic Organic Compound Adsorption
The aromatic PS/DVB surface can adsorb hydrophobic organic molecules from aqueous or mixed-solvent systems.
Potential targets include:
Aromatic compounds
Phenolic compounds
Organic colorants
Hydrophobic impurities
Pharmaceutical intermediates
Natural product components
Industrial Separation and Purification
Suitable for process research involving the capture, concentration or removal of organic compounds.
Natural Product Purification
Can be evaluated for the adsorption and purification of plant extracts, fermentation products and other complex mixtures.
Pharmaceutical Process Development
Suitable for adsorbent screening, impurity removal and intermediate purification research.
Environmental Treatment Research
Can be evaluated for removing selected organic pollutants, dyes and hydrophobic contaminants from water.
Batch Adsorption
The large particles are convenient for stirred adsorption processes followed by filtration or sedimentation.
Low-Pressure Column Separation
Suitable for gravity-flow columns and low-pressure packed beds used in laboratory or process development.
Functional Carrier Development
The porous PS/DVB matrix can be modified with functional groups, ligands, catalysts or biomolecules.
Immobilized Enzyme Carrier Research
After suitable activation or functionalization, the porous particles can be evaluated as carriers for enzyme immobilization.
Solid-Phase Synthesis Support
Customized functionalized versions may be evaluated as polymer supports for chemical or biomolecule synthesis.
How the Porous PS/DVB Matrix Works
The polystyrene matrix provides an aromatic and hydrophobic surface.
Hydrophobic analytes can interact with the external surface and the internal pore surface of the microspheres. The porous structure increases the accessible interaction area compared with nonporous particles.
Divinylbenzene forms a crosslinked network that strengthens the polymer matrix and helps control swelling and particle deformation.
Adsorption performance depends on:
Molecular size
Molecular hydrophobicity
Pore accessibility
Solvent composition
Contact time
Temperature
Sample concentration
Surface functionalization
Application conditions should be optimized for each target compound.
Advantages of the Crosslinked PS/DVB Matrix
Hydrophobic Adsorption
The standard polymer surface is suitable for capturing nonpolar and moderately hydrophobic compounds.
No Silanol Groups
PS/DVB particles do not contain the residual silanol groups commonly associated with silica-based materials.
Flexible Solvent Selection
The crosslinked polymer matrix can be evaluated with different aqueous and organic solvent systems after compatibility validation.
Functionalization Potential
The matrix can be chemically modified to introduce charged, polar, reactive or application-specific groups.
Reusable Process Development
The stable particle structure can be evaluated for repeated adsorption, washing and regeneration cycles.
Column Packing and Process Use
PS/DVB200UM-300A can be used in:
Gravity-flow columns
Low-pressure chromatography columns
Adsorption cartridges
Fixed-bed adsorption systems
Batch adsorption tanks
Sample-cleanup devices
Process-development columns
Custom purification equipment
General Column Packing Procedure
Select a compatible slurry liquid.
Fully wet and disperse the microspheres.
Remove visible aggregates and trapped air.
Prepare a uniform particle slurry.
Transfer the slurry into the column.
Allow the particles to settle uniformly.
Apply gentle flow to stabilize the packed bed.
Equilibrate with the selected working solution.
Check bed uniformity and flow resistance.
Load the sample and collect the required fractions.
Column dimensions, bed height and flow rate should be optimized according to the sample and process objective.
General Batch Adsorption Procedure
Add the required amount of microspheres to the sample.
Mix gently to maintain particle suspension.
Allow sufficient contact time for adsorption.
Separate the microspheres by filtration or sedimentation.
Wash the particles when required.
Elute or regenerate using a validated solution.
Analyze adsorption and recovery performance.
The resin-to-sample ratio, mixing speed, contact time and elution conditions should be optimized experimentally.
Surface Functionalization Options
SHBC can customize PS/DVB microspheres with different surface chemistries.
Available options may include:
Sulfonic acid groups
Quaternary ammonium groups
Amino groups
Carboxyl groups
Hydroxyl groups
Epoxy groups
Aldehyde groups
Hydrophilic coatings
Affinity ligands
Catalyst groups
Custom functional molecules
Functionalized versions can be developed for ion exchange, affinity capture, catalysis, enzyme immobilization or specialized adsorption.
Why Choose SHBC
Controlled Particle Manufacturing
SHBC applies controlled polymerization, pore formation and particle-classification processes.
Defined Particle and Pore Size
The combination of 200µm particles and 300Å pores is designed for adsorption and low-pressure separation applications.
Flexible Product Customization
Particle size, pore size, crosslinking degree, surface chemistry and packaging can be adjusted according to project requirements.
Reliable Batch Supply
Controlled manufacturing and inspection support consistent product performance between production batches.
Scale-Up Manufacturing
SHBC supports laboratory testing, pilot evaluation and industrial bulk production.
Technical Support
Technical assistance is available for product selection, adsorption testing, column packing and surface functionalization.
Custom and Bulk Supply
Shanghai SanYu Biotechnology Co., Ltd. supplies porous PS/DVB microspheres to research institutes, pharmaceutical companies, environmental technology companies and separation-material manufacturers.
Available customization includes:
Custom particle size
Custom pore size
Custom pore volume
Custom specific surface area
Custom crosslinking degree
Surface functionalization
Custom supply form
Custom packaging
Pilot-scale production
Bulk manufacturing
OEM and ODM services
Batch quality documentation
Please provide the target compound, solvent system, separation method and estimated order quantity when requesting a quotation.
Frequently Asked Questions
What is PS/DVB200UM-300A?
It is a porous crosslinked PS/DVB microsphere with a nominal particle size of 200µm and a pore size of 300Å.
What does 300Å mean?
It represents a nominal pore diameter of approximately 30nm inside the polymer particles.
What is the advantage of 200µm particles?
The larger particle size supports convenient filtration, washing, recovery and low-pressure column operation.
Is the surface hydrophobic?
Yes. The standard non-functionalized PS/DVB surface is hydrophobic.
What compounds can be adsorbed?
The material can be evaluated for aromatic compounds, phenols, colorants, pharmaceutical intermediates and other hydrophobic organic molecules.
Can it be used for protein purification?
The standard hydrophobic form may adsorb some proteins nonspecifically. For selective protein purification, a suitable hydrophilic coating or affinity ligand is recommended.
Can it be used for ion exchange?
The standard material does not contain ion-exchange groups. Sulfonic acid, amino or quaternary ammonium groups can be customized.
Can it be used as an enzyme carrier?
Yes. After suitable activation or surface functionalization, it can be evaluated for enzyme immobilization.
Is it suitable for HPLC?
The 200µm particle size is mainly suited to low-pressure columns, packed-bed adsorption and batch separation rather than conventional high-pressure analytical HPLC.
Can SHBC customize the pore size?
Yes. Particle size, pore size, crosslinking degree and surface chemistry can be customized.
Is bulk manufacturing available?
Yes. SHBC supports samples, pilot-scale quantities and bulk production.
Storage and Handling
Store PS/DVB200UM-300A according to the SHBC technical documentation.
Keep the product tightly sealed and protected from contamination. Avoid exposure to unvalidated solvents, temperatures and oxidizing chemicals. Follow appropriate safety procedures when handling dry polymer particles.
Request a Sample or Quotation
Contact Shanghai SanYu Biotechnology Co., Ltd. for samples, technical documents, customized specifications or bulk pricing.
Product: 200µm Porous Crosslinked PS/DVB Microspheres
Catalog Number: PS/DVB200UM-300A
Brand: SHBC
Particle Size: 200µm
Pore Size: 300Å
Matrix: Polystyrene/Divinylbenzene
Manufacturer: Shanghai SanYu Biotechnology Co., Ltd.
For research and industrial separation use only.