Products
SHBC provides colored microspheres, fluorescent microspheres, magnetic beads, silica microspheres, chromatography packing microspheres and biological reagents for diagnostic assay development, nucleic acid extraction, protein purification and separation applications.
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PS/DVB3UM
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SHBC
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3µm
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1g 10g 50g 100g 1000g
300nm Crosslinked PS/DVB Microspheres 5%
SHBC 300nm Crosslinked PS/DVB Microspheres are uniform polymer particles manufactured from polystyrene and divinylbenzene.
The DVB-crosslinked structure provides better dimensional stability and chemical resistance than conventional non-crosslinked polystyrene particles. Supplied as a 5% aqueous suspension, these microspheres are suitable for immunoassay research, particle calibration, material development and surface modification.
Product Overview
SHBC PS/DVB 300nm microspheres combine the optical properties of polystyrene with the structural stability of a crosslinked polymer network.
The hydrophobic particle surface supports physical adsorption of proteins and other biomolecules. The microspheres may also be further functionalized for covalent coupling or specialized material applications.
Key Features and Benefits
Nominal particle size of 300nm
Polystyrene-divinylbenzene matrix
Crosslinked polymer structure
5% solid concentration
Uniform spherical morphology
Hydrophobic particle surface
Improved structural stability
Good resistance to acids, bases and alcohols
Suitable for physical protein adsorption
Suitable for surface modification
Stable aqueous suspension
Custom and bulk supply available
Product Specifications
Parameter | Specification |
|---|---|
Product Name | Crosslinked PS/DVB Microspheres |
Alternative Name | Poly(styrene-co-divinylbenzene) Microspheres |
Brand | SHBC |
Particle Size | 300nm |
Solid Content | 5% |
Matrix | Polystyrene/Divinylbenzene |
Surface | Non-functionalized hydrophobic surface |
Product Form | Aqueous microsphere suspension |
Manufacturer | Shanghai SanYu Biotechnology Co., Ltd. |
Intended Use | Research and industrial raw material |
Particle size distribution, crosslinking level, dispersion medium and surface chemistry can be customized according to project requirements.
Why Use PS/DVB Crosslinked Microspheres
Improved Particle Stability
Divinylbenzene forms a crosslinked polymer network that helps the particles maintain their shape during processing and repeated washing.
Better Chemical Resistance
The crosslinked structure provides better resistance to many chemical environments than non-crosslinked polystyrene microspheres.
Stable Hydrophobic Surface
The PS/DVB surface is suitable for physical adsorption of proteins, antibodies, antigens and other hydrophobic molecules.
Uniform Particle Performance
Controlled particle manufacturing supports consistent size, suspension behavior and batch-to-batch performance.
Flexible Surface Modification
The microspheres can be further modified with carboxyl, amino, epoxy or other functional groups for specific coupling applications.
Recommended Applications
Immunoassay Development
Suitable for latex agglutination, particle-based immunoassays and other diagnostic reagent research.
Protein and Antibody Adsorption
The hydrophobic surface can physically adsorb antibodies, antigens, proteins and other biomolecules.
Turbidimetric and Nephelometric Assays
The 300nm particles can be evaluated for optical detection systems based on light scattering or turbidity changes.
Particle Size Standards
Suitable for calibration and performance verification of particle analyzers, flow cytometers and optical detection instruments.
Surface Modification Research
Can be used as a base particle for introducing carboxyl, amino, epoxy, aldehyde or other reactive groups.
Colloidal and Polymer Research
Suitable for studies involving particle dispersion, aggregation, surface charge and polymer colloid behavior.
Photonic and Optical Materials
Uniform PS/DVB microspheres can be evaluated for colloidal assembly, optical scattering and photonic material research.
Coatings and Composite Materials
Can be used as polymer fillers, surface-texture modifiers or functional additives in coatings and composite systems.
Environmental and Flow Tracing
Suitable for particle tracking, flow visualization and environmental transport research.
Template Material
Can be used as a sacrificial or structural template for preparing hollow particles, porous materials and composite structures.
Advantages of 300nm Particle Size
The 300nm diameter provides a balance between surface area, light-scattering performance and suspension stability.
Compared with larger microspheres, 300nm particles provide more particle surface area at the same solid concentration. They are suitable for optical assays, biomolecule adsorption, colloidal research and nanostructured material development.
Physical Adsorption of Biomolecules
Proteins and antibodies may adsorb onto the hydrophobic PS/DVB surface through hydrophobic and other non-covalent interactions.
A general adsorption workflow includes:
Mix the microsphere suspension thoroughly.
Wash the particles with a suitable buffer.
Add the antibody, antigen or protein.
Incubate under optimized conditions.
Block the remaining particle surface.
Wash away unbound biomolecules.
Resuspend the conjugated particles in storage buffer.
Protein concentration, pH, ionic strength, incubation time and blocking agent should be optimized for each application.
Surface Modification Options
SHBC can provide customized functionalized PS/DVB microspheres for covalent biomolecule coupling.
Available surface groups may include:
Carboxyl
Amino
Epoxy
Aldehyde
Hydroxyl
Sulfonate
Streptavidin
Custom functional ligands
Surface functionalization should be selected according to the target molecule and coupling method.
Handling and Dispersion
Mix the microsphere suspension thoroughly before sampling.
Recommended handling methods include:
Gentle vortex mixing
Manual shaking
Short ultrasonic dispersion
Dilution with filtered purified water
Avoidance of freezing
Prevention of microbial contamination
Use of clean laboratory containers
Excessive ultrasonication or high-shear mixing should be avoided unless validated for the final application.
Storage Recommendations
Store the microspheres according to the conditions stated in the SHBC technical documentation.
Keep the container tightly sealed. Do not allow the suspension to freeze or dry. Mix thoroughly before use and avoid introducing particles, microorganisms or incompatible chemicals into the original container.
Why Choose SHBC PS/DVB Microspheres
Controlled Particle Manufacturing
SHBC applies controlled polymerization and particle classification processes to support uniform 300nm particle size.
Stable Crosslinked Matrix
The PS/DVB structure provides improved particle strength and chemical stability for research and industrial applications.
Reliable Batch Consistency
Controlled production and quality inspection support consistent particle size, concentration and suspension performance.
Flexible Surface Chemistry
Non-functionalized and functionalized PS/DVB microspheres are available for different coupling and material-development requirements.
Scale-Up Manufacturing
SHBC supports laboratory samples, pilot-scale evaluation and industrial batch production.
Technical Support
Technical assistance is available for particle selection, dispersion, physical adsorption, surface modification and application development.
Custom and Bulk Supply
Shanghai SanYu Biotechnology Co., Ltd. supplies PS/DVB microspheres to universities, research institutions, diagnostic reagent companies and material manufacturers.
Available services include:
Custom particle size
Custom crosslinking level
Custom solid concentration
Custom surface functional groups
Custom dispersion medium
Sample evaluation
Pilot-scale production
Bulk manufacturing
OEM and ODM services
Custom packaging
Batch quality documentation
Please provide the required particle size, surface group, concentration, application and estimated order volume when requesting a quotation.
Frequently Asked Questions
What are PS/DVB microspheres?
PS/DVB microspheres are polymer particles made from polystyrene crosslinked with divinylbenzene.
What is the particle size?
The nominal particle size is 300nm.
What is the solid content?
The standard solid content is 5%.
What does DVB crosslinking provide?
DVB forms a crosslinked polymer structure that improves particle stability and resistance to chemical and processing conditions.
Is the particle surface hydrophobic?
Yes. Non-functionalized PS/DVB microspheres have a hydrophobic polymer surface.
Can antibodies be attached to the particles?
Antibodies and proteins can be physically adsorbed onto the hydrophobic surface. Functionalized versions can also be produced for covalent coupling.
Are the microspheres suitable for immunoassays?
Yes. They can be evaluated for latex agglutination, turbidimetric assays, nephelometric assays and other particle-based immunoassays.
Can SHBC customize the surface?
Yes. Carboxyl, amino, epoxy and other functionalized surfaces can be customized.
Can the concentration be customized?
Yes. Solid concentration and dispersion medium can be adjusted according to project requirements.
Is bulk manufacturing available?
Yes. SHBC supports samples, pilot-scale orders and bulk production.
Request a Sample or Quotation
Contact Shanghai SanYu Biotechnology Co., Ltd. for samples, technical documentation, customized specifications or bulk pricing.
Product: 300nm Crosslinked PS/DVB Microspheres
Brand: SHBC
Particle Size: 300nm
Solid Content: 5%
Matrix: Polystyrene/Divinylbenzene
Surface: Hydrophobic, non-functionalized
Manufacturer: Shanghai SanYu Biotechnology Co., Ltd.
For research and industrial raw material use only.