Your Trusted Microsphere Manufacturer for Diagnostic Innovation

Magnetic Beads for IVD & Bioseparation

Functionalized beads for nucleic acid extraction, molecular diagnostics, purification and automated bioseparation workflows.

Need help selecting a bead?

Share two details for a tailored starting point.
Particle Size Control

Custom particle size

Match separation and suspension needs

Material & Surface Options

Surface chemistry

Standard and functionalized bead options

Standard & Custom

OEM & scale-up

From evaluation sample to routine supply

Technical Documents

Technical support

Selection guidance for your workflow

PRODUCT PLATFORM

Magnetic Bead Solutions By Surface Chemistry

Start with your binding principle. Then confirm particle size, buffer, solids content and workflow requirements with our technical team.

KEY BENIFITS

Choose Magnetic Beads By Application

Not sure which surface chemistry fits? Start with your target, sample type and process format.

NUCLEIC

Nucleic Acid Extraction

Build a starting material around your sample, lysis and binding chemistry, target nucleic acid and automation format.

IVD

Immunoassay & IVD

Carboxyl, NHS, Tosyl or Streptavidin options for immobilization, capture and assay development.


PRO

Protein Purification

Affinity and functionalized magnetic media for tagged proteins, antibodies and protein complexes.

AUTO

High-Throughput Automation

Evaluate magnetic response, settling, resuspension and consistency for plate-based or magnetic-rod workflows.

CONJ

Biomolecule Conjugation

Match surface chemistry and coupling conditions to proteins, antibodies, oligos, enzymes or peptides.

CELL

Cell Separation

Define the target cell, sample matrix, capture strategy and downstream analysis before selecting a bead.

Compare Binding Principles Before Choosing A Bead

Use this table to frame the first technical conversation. Final specifications should be confirmed for the selected product.
Bead typeBinding or coupling principleTypical useInformation needed
SilicaNucleic acid adsorptionDNA and RNA extractionSample, buffers and automation format
CarboxylEDC/NHS covalent couplingProtein, antibody or oligo immobilizationSize, target loading and blocking
StreptavidinBiotin-streptavidin affinityBiotinylated molecule captureBinding capacity and workflow volume
NHSDirect reaction with primary aminesFast protein or antibody couplingCoupling buffer and quenching
AminoCrosslinker-based couplingSurface modification and conjugationCrosslinker and functional target
EpoxyReaction with nucleophilic groupsProtein or enzyme immobilizationpH, time and molecule stability
NickelMetal affinity captureHis-tag protein purificationExpression system and purity target
TosylActivated surface couplingAntibody or protein immobilizationTarget molecule and required loading

Need help translating your workflow into bead requirements?

Key Technical Specifications For Evaluation

Review the bead in the context of your assay conditions. A single isolated number rarely predicts workflow performance.

Technical documents

Ask about available TDS, COA, SDS, test methods and batch-specific records.

Particle size

Nominal size, distribution and the measurement method used.

Magnetic behavior

Separation response, recovery and resuspension under defined conditions.

Surface chemistry

Functional group, ligand or activation state and related test method.

Binding capacity

Target-specific capacity with the molecule and test conditions identified.

Product format

Solids concentration, buffer composition, package and preservative if applicable.

Compatibility

Relevant pH, salts, surfactants, magnetic hardware and automation formats.

Storage

Temperature, shelf life and any freeze-thaw restrictions.

CUSTOM & OEM

A Practical Path From Requirement To Routine Supply

Start from a standard material when possible. Customize the attributes that materially affect your workflow.

Requirement review

Application, sample, target, particle needs, process volume and forecast.

Material recommendation

Select a standard bead or define a focused custom development plan.

Sample & evaluation

Evaluate samples with available specifications and suggested starting conditions.

Workflow optimization

Review recovery, background, separation, coupling and resuspension feedback.

Scale-up & validation

Align acceptance criteria, packaging and batch documentation before expansion.

Routine supply

Maintain traceability, agreed records and ongoing technical communication.

10004 (3)

WHY CHOOSE SHBC

Quality Evidence That Supports Supplier Evaluation

Ask for product-specific evidence and test conditions. Claims should be tied to the bead, batch and intended workflow.

Particle distribution

DLS, microscopy or another product-appropriate method.

Magnetic separation

Defined magnetic field, sample volume and recovery conditions.

Surface functionality

Chemical or functional testing relevant to the surface.

Batch consistency

Comparable results across agreed critical quality attributes.

QUALITY & DOCUMENTATION

Why Technical Buyers Evaluate SHBC

A focused magnetic bead conversation backed by a broader microsphere and manufacturing platform.

01

Complete bead portfolio

Surface chemistries and affinity formats for diagnostic, purification and separation workflows.

02

Selection support

Recommendations based on target, sample, chemistry, format and scale.

03

Focused customization

Define particle, surface, magnetic, buffer and packaging attributes that matter.

04

Scale-up planning

Move from evaluation material toward agreed quality criteria and routine supply.

TECHNICAL FAQ

Frequently Asked Questions About Magnetic Beads

  • What types of magnetic beads does SHBC offer?

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    The portfolio includes silica, carboxyl, streptavidin, NHS, amino, epoxy, nickel, tosyl and cell sorting magnetic beads. Availability and specifications vary by product.

  • How do I choose between silica, carboxyl and streptavidin beads?

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    Silica is commonly evaluated for nucleic acid purification, carboxyl for covalent immobilization through EDC/NHS chemistry, and streptavidin for affinity capture of biotinylated molecules.

  • What particle sizes and concentrations are available?

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    Available sizes and solids concentrations depend on the bead type. Share your workflow and preferred format so the team can confirm current options.

  • Can surface chemistry or magnetic response be customized?

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    Custom development can address particle size, surface chemistry, magnetic response, buffer, solids content and packaging, subject to technical review.

  • Can the beads support automated extraction workflows?

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    Automation fit should be evaluated against settling, resuspension, magnetic hardware, plate or rod format, liquid handling and process timing.

  • What data can be provided for evaluation?

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    Ask about available particle size, magnetic separation, surface functionality, binding, solids, storage and batch-specific documentation for the selected product.

  • Are samples available for method development?

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    Use the sample and quote request to share your application, target and required format. The team will confirm suitable evaluation material and availability.

  • What information should I provide for a recommendation?

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    Include the application, sample type, target molecule, preferred bead type or size, process volume, automation format and expected quantity when known.