Microspheres for IVD & POCT Assay Development

Color Carboxyl Latex Microspheres are dyed polystyrene particles functionalized with surface carboxyl groups. They are specifically developed for lateral flow immunoassays and rapid diagnostic tests. Their vivid colors provide clear visual signals, while the carboxyl groups enable stable covalent coupling with antibodies or proteins, resulting in high sensitivity, excellent reproducibility, and reliable qualitative or quantitative detection.

Compared with colloidal gold, colored latex microspheres provide stronger color intensity, better stability, and multiple color options for multiplex assays. Their surface carboxyl groups enable efficient covalent antibody conjugation, reducing nonspecific adsorption and improving assay sensitivity, signal consistency, and long-term storage performance.

Yes. The abundant carboxyl groups on the particle surface are suitable for EDC/NHS activation, allowing stable covalent bonding with antibodies, antigens, proteins, peptides, enzymes, and amino-modified biomolecules. This chemistry provides high coupling efficiency while maintaining excellent biological activity for diagnostic applications.

Besides lateral flow assays, these microspheres are suitable for latex agglutination tests, immunoassays, biosensor development, protein immobilization, molecular diagnostics, reagent development, and laboratory research. They are widely used by IVD manufacturers, biotechnology companies, universities, and research institutes.

Standard colors include deep red, deep blue, and deep purple. Multiple colors can be selected for multiplex assays or dual-target detection, allowing clear visual discrimination between different biomarkers. Custom colors may also be available depending on project requirements and order quantity.

The dyes are encapsulated inside the polystyrene particles rather than simply adsorbed on the surface, providing excellent color stability and minimizing dye leakage. Under recommended storage conditions, the microspheres maintain consistent performance during transportation, long-term storage, and routine laboratory use.

Yes. We provide comprehensive OEM and customization services, including particle size, solid content, color selection, buffer system, surface functional groups, and concentration. Customized products help customers optimize sensitivity, flow performance, and overall assay reproducibility.

Uniform particle size distribution, stable surface chemistry, and efficient antibody conjugation contribute to strong and consistent signal generation. Optimized surface properties help reduce nonspecific adsorption, resulting in lower background noise, higher sensitivity, and better batch-to-batch reproducibility.

Our customers include IVD reagent manufacturers, biotechnology companies, pharmaceutical enterprises, universities, research institutes, CRO laboratories, and diagnostic kit developers. The microspheres are widely used in medical diagnostics, life science research, food safety testing, and veterinary diagnostics.

SHBC provides highly uniform colored latex microspheres with stable quality, excellent batch consistency, and reliable surface chemistry. We support OEM customization, technical consultation, antibody conjugation optimization, and scalable manufacturing, helping customers accelerate product development and commercial production.