Product Overview of MC5100UM-10 Carboxyl Magnetic Beads

MC100UM-10 is a high-performance 100µm carboxyl magnetic bead designed for immunoassay reagent development, chemiluminescent immunoassay (CLIA), immunoprecipitation, cell magnetic separation, and nucleic acid capture applications.

The magnetic beads contain abundant surface carboxyl groups (-COOH), which can react with primary amino groups of proteins, antibodies, peptides, and nucleic acids through EDC/NHS coupling chemistry to form stable amide bonds.

With a large particle size, high surface loading capacity, rapid magnetic response, and excellent separation efficiency, MC100UM-10 provides an efficient magnetic carrier solution for biotechnology companies and diagnostic reagent manufacturers requiring reliable materials for research development and industrial-scale production.

Key Features of 100µm COOH Magnetic Beads

Rich Carboxyl Functional Groups for Biomolecule Coupling

The surface of MC100UM-10 is modified with abundant carboxyl groups, enabling efficient covalent immobilization of biological molecules.

Suitable for coupling:

• Antibodies

• Antigens

• Proteins

• Peptides

• Enzymes

• Nucleic acids

The stable amide bond formed through EDC/NHS activation provides reliable immobilization performance for diagnostic applications.

Large Particle Size with High Binding Capacity

The 100µm particle size provides:

• Large surface area

• High biomolecule loading capacity

• Efficient target capture

• Improved separation performance

Large magnetic beads are especially suitable for applications requiring rapid recovery and efficient magnetic separation.

Fast Magnetic Separation Performance

MC100UM-10 contains a superparamagnetic core that enables quick response under an external magnetic field.

Advantages include:

✓ Rapid separation
✓ Easy washing process
✓ Improved workflow efficiency
✓ Compatibility with manual and automated platforms

Low Non-Specific Adsorption

The optimized polymer surface structure helps reduce unwanted adsorption of background substances.

Benefits:

• Improved assay accuracy

• Reduced background signal

• Better reproducibility

• Stable experimental performance

Technical Specifications of MC100UM-10

Carboxyl Magnetic Beads for Chemiluminescent Immunoassay

MC100UM-10 can be used as a magnetic solid-phase carrier in chemiluminescent immunoassay reagent development.

The carboxyl-functional surface enables efficient antibody or protein immobilization, supporting:

• Magnetic particle chemiluminescence immunoassay

• Electrochemiluminescence assay development

• Diagnostic reagent optimization

• Automated immunoassay platforms

The high loading capacity and rapid magnetic separation characteristics help improve assay workflow and production consistency.

Applications in Immunoprecipitation and Cell Magnetic Separation

Immunoprecipitation (IP)

Carboxyl magnetic beads provide an effective carrier for capturing target proteins and biomolecules through antibody coupling.

Applications include:

• Protein enrichment

• Target molecule isolation

• Immunocomplex purification

Cell Magnetic Separation

The magnetic beads can be functionalized with antibodies or ligands for selective cell capture and separation.

Applications:

• Cell enrichment

• Cell isolation

• Biological sample preparation

Nucleic Acid Capture Using Carboxyl Magnetic Beads

Due to their functional surface chemistry, MC100UM-10 magnetic beads can support nucleic acid-related applications.

Potential uses include:

• DNA capture

• RNA purification

• Molecular biology sample preparation

• Biomolecule enrichment

The stable coupling chemistry provides reliable performance for research and development workflows.

Advantages of SHBC Functionalized Magnetic Microspheres

SHBC carboxyl magnetic beads utilize advanced microsphere manufacturing technology to provide:

✓ Uniform particle size distribution
✓ Stable magnetic response
✓ High surface functional density
✓ Excellent suspension stability
✓ Low batch-to-batch variation
✓ Reliable coupling performance

Our magnetic beads are widely used by:

• IVD manufacturers

• Diagnostic reagent developers

• Biotechnology companies

• Research laboratories

Bulk Production and OEM Customization of Magnetic Beads

SHBC provides professional magnetic bead manufacturing services for customers requiring research-scale and commercial-scale supply.

Customization options include:

• Particle size customization

• Surface functional group modification

• Solid content adjustment

• Buffer optimization

• Packaging customization

• Bulk manufacturing support

We support customers from assay development to large-scale reagent production.

Frequently Asked Questions About 100µm Carboxyl Magnetic Beads

What are 100µm carboxyl magnetic beads used for?

100µm carboxyl magnetic beads are used for immunoassay reagent development, chemiluminescent immunoassay, immunoprecipitation, cell separation, and nucleic acid capture applications.

How do carboxyl magnetic beads couple with proteins?

The surface carboxyl groups are activated using EDC/NHS chemistry and react with amino groups of proteins or antibodies to form stable amide bonds.

Why choose large-size magnetic beads?

Large magnetic beads provide higher loading capacity and faster magnetic separation, making them suitable for sample preparation and biological capture applications.

Can MagCOOH5100UM-10 be supplied for bulk production?

Yes. SHBC provides bulk supply and OEM customization services for diagnostic reagent manufacturers and biotechnology companies.

What is the solid content of MC100UM-10?

The standard solid content of MC100UM-10 is 5%.