Product Overview of MC100NM-10 Carboxyl Magnetic Beads

MC100NM-10 is a high-performance 100nm carboxyl magnetic bead designed for immunoassay development, chemiluminescent immunoassays (CLIA), and diagnostic reagent manufacturing.

The magnetic microspheres feature abundant surface carboxyl groups (-COOH), enabling efficient covalent coupling with proteins, antibodies, antigens, peptides, and other biomolecules through EDC/NHS chemistry.

With uniform particle size distribution, strong magnetic response, and excellent suspension stability, MC100NM-10 provides reliable performance for high-sensitivity immunoassay platforms and large-scale IVD production.

Key Features of 100nm COOH Magnetic Beads

High Surface Carboxyl Density

The surface of MC100NM-10 contains rich carboxyl functional groups, providing efficient biomolecule immobilization and stable coupling performance.

Excellent Particle Uniformity

The 100nm magnetic beads feature narrow particle size distribution, ensuring consistent assay performance and improved batch-to-batch reproducibility.

Fast Magnetic Separation

The superparamagnetic core enables rapid magnetic response, allowing efficient separation and washing during immunoassay workflows.

Low Non-Specific Binding

The optimized polymer coating structure helps reduce non-specific adsorption, improving signal-to-background ratio and assay sensitivity.

Stable Suspension Performance

The microspheres maintain excellent dispersion stability during storage, handling, and automated diagnostic processes.

Technical Specifications of MagCOOH100NM

Applications in Immunoassay and IVD Development

MC100NM-10 carboxyl magnetic beads are widely used by biotechnology companies, diagnostic reagent manufacturers, and research institutions for:

Chemiluminescent Immunoassay (CLIA)

Used as a solid-phase carrier for antibody or antigen immobilization in high-sensitivity chemiluminescence detection systems.

Immunoassay Reagent Development

Suitable for developing diagnostic kits requiring stable biomolecule coupling and efficient magnetic separation.

Antibody and Protein Coupling

The surface carboxyl groups enable covalent binding with primary amino groups of antibodies, proteins, peptides, and enzymes.

Biomarker Detection

Applicable for research and development of immunodiagnostic assays for proteins, hormones, infectious diseases, and molecular biomarkers.

Automated IVD Platforms

Compatible with automated immunoassay instruments requiring highly uniform magnetic particles and reliable batch consistency.

Advantages for CLIA and Diagnostic Reagent Manufacturers

For companies producing immunodiagnostic reagents, magnetic bead performance directly affects assay sensitivity, stability, and production consistency.

MC100NM-10 provides:

• Reliable antibody coupling efficiency

• Reduced background signal

• Improved assay reproducibility

• Consistent magnetic separation performance

• Stable supply for commercial production

• Compatibility with automated CLIA systems

These characteristics make it an ideal magnetic bead solution for IVD manufacturers developing high-performance immunoassay products.

Why Choose SHBC Carboxyl Magnetic Beads

SHBC develops and manufactures functional magnetic microspheres for biomedical and diagnostic applications.

Our carboxyl magnetic beads utilize an advanced sandwich magnetic structure, consisting of:

• Porous polymer core

• Magnetic layer

• Functional polymer shell

This unique structure provides:

✓ High magnetic responsiveness
✓ Uniform particle size distribution
✓ Excellent suspension stability
✓ Low non-specific adsorption
✓ High biomolecule coupling efficiency
✓ Reliable batch-to-batch consistency

SHBC supports global customers with customized magnetic bead solutions for research, diagnostic development, and industrial manufacturing.

Customization and OEM Manufacturing Services

SHBC provides customized magnetic bead solutions according to customer requirements, including:

• Particle size customization

• Surface functional group modification

• Solid content adjustment

• Buffer formulation optimization

• Bulk production supply

Our magnetic beads are available for research institutions, IVD companies, diagnostic reagent manufacturers, and biotechnology enterprises requiring stable large-scale supply.

Frequently Asked Questions About 100nm Carboxyl Magnetic Beads

What are 100nm carboxyl magnetic beads used for?

100nm carboxyl magnetic beads are mainly used for immunoassays, CLIA reagent development, antibody coupling, protein immobilization, and diagnostic assay manufacturing.

How do carboxyl magnetic beads bind antibodies?

Carboxyl magnetic beads bind antibodies through EDC/NHS coupling chemistry, forming stable amide bonds between bead surface carboxyl groups and antibody amino groups.

Why choose 100nm magnetic beads for immunoassays?

100nm magnetic beads provide a balance between high surface area, efficient biomolecule coupling, and rapid magnetic separation, making them suitable for sensitive immunoassay applications.

Can SHBC provide bulk magnetic bead supply?

Yes. SHBC provides OEM and bulk manufacturing services for diagnostic companies and biotechnology manufacturers requiring consistent magnetic bead production.