1um Epoxy Silicate Microspheres ESi1UM-10 5%

1µm Epoxy Silicate Microspheres ESi1UM-10

SHBC ESi1UM-10 is a 1µm epoxy-functionalized silicate microsphere suspension with 5% solids. The reactive epoxy surface is designed for covalent immobilization of proteins, antibodies, peptides, enzymes and amino-modified biomolecules.

These microspheres combine a stable inorganic silica matrix with reactive surface epoxy groups, making them suitable for bioassay development, biomolecule immobilization, separation research and functional material preparation.

Product Overview

ESi1UM-10 provides a convenient solid carrier for researchers and manufacturers requiring stable 1µm epoxy silica microspheres.

The surface epoxy groups can react with primary amino groups on biomolecules, forming stable covalent bonds without requiring a separate EDC/NHS activation step.

Key Features and Benefits

• Uniform 1µm particle size

• Reactive epoxy-functionalized surface

• Stable silicate and silica particle matrix

• Suitable for direct biomolecule immobilization

• Strong covalent binding stability

• Good suspension and handling performance

• Suitable for research and process development

• Reliable batch-to-batch production

• Custom concentration and packaging available

Product Specifications

How Epoxy Silicate Microspheres Work

Epoxy groups on the microsphere surface can react with nucleophilic functional groups, particularly primary amino groups.

Antibodies, proteins, peptides, enzymes or amino-modified oligonucleotides can therefore be covalently immobilized on the particle surface. Covalent attachment provides better binding stability than physical adsorption and helps reduce biomolecule loss during repeated washing or separation steps.

Recommended Applications

Antibody and Protein Immobilization

Suitable for covalent coupling of antibodies, antigens, recombinant proteins and peptides used in assay development.

Enzyme Immobilization

The stable silica matrix provides a solid support for enzyme immobilization, biocatalyst preparation and repeated-use reaction systems.

Nucleic Acid Probe Coupling

Can be used with amino-modified DNA, RNA or oligonucleotide probes for nucleic acid research and assay carrier development.

Bioassay Carrier Development

Suitable for developing microsphere-based immunoassays, diagnostic research systems and functional particle reagents.

Separation and Purification Research

Can be used as a functional solid phase for affinity separation, chromatography media research and biomolecule purification studies.

Surface Modification Research

The epoxy surface can be further modified with amino-containing molecules, polymers, ligands or other functional materials.

Biomolecule Coupling Workflow

1. Fully disperse the microsphere suspension before use.

2. Wash the microspheres with a compatible reaction buffer.

3. Add the amino-containing antibody, protein, enzyme or probe.

4. Allow sufficient reaction time for covalent coupling.

5. Block the remaining epoxy groups when required.

6. Wash away unbound biomolecules.

7. Resuspend the conjugated microspheres in a suitable storage buffer.

Coupling conditions should be optimized according to the biomolecule, buffer composition, target loading and final application.

Why Choose SHBC Epoxy Silicate Microspheres

Reactive Epoxy Surface

The functionalized surface supports stable covalent immobilization of amino-containing biomolecules.

Stable Silica Matrix

The inorganic particle structure provides good mechanical and chemical stability for research and industrial development.

Controlled Particle Production

Controlled manufacturing supports particle-size consistency and reliable performance between production batches.

Flexible Customization

Particle size, surface functionality, solid content, packaging volume and coupling services can be customized according to project requirements.

Bulk Manufacturing Support

Shanghai SanYu Biotechnology Co., Ltd. supports laboratory evaluation, pilot-scale testing and bulk supply for research institutions, biotechnology companies and diagnostic reagent manufacturers.

Custom and Bulk Supply

SHBC provides epoxy-functionalized silicate microspheres for research, product development and industrial-scale production.

Available services include:

• Custom particle size

• Custom solid concentration

• Surface group optimization

• Biomolecule coupling support

• Sample evaluation

• OEM and ODM production

• Bulk packaging

• Batch consistency documentation

Contact SHBC with your required particle size, concentration, application and estimated order quantity.

Frequently Asked Questions

What are 1µm Epoxy Silicate Microspheres?

They are 1µm silica-based microspheres modified with reactive epoxy groups for covalent immobilization of amino-containing biomolecules and functional compounds.

What molecules can be coupled to ESi1UM-10?

Typical targets include antibodies, proteins, peptides, enzymes, amino-modified DNA, amino-modified RNA and amino-containing ligands.

Do epoxy microspheres require EDC/NHS activation?

Normally, epoxy groups can react directly with suitable nucleophilic groups, especially primary amino groups. A separate carbodiimide activation step is generally not required.

What is the solid content of ESi1UM-10?

The standard solid content is 5%.

Can SHBC customize the particle concentration?

Yes. Particle size, concentration, surface chemistry and packaging can be customized according to the application.

Are these microspheres suitable for bulk production?

Yes. SHBC supports sample testing, pilot-scale orders and batch manufacturing for research and industrial customers.

Storage and Handling

Store the product under the conditions stated in the product documentation. Avoid freezing, contamination and prolonged exposure to unsuitable pH conditions.

Mix gently or use appropriate dispersion methods before sampling. Users should validate storage stability and coupling performance under their own experimental conditions.

Request a Sample or Quotation

Contact Shanghai SanYu Biotechnology Co., Ltd. for samples, technical information, customization or bulk pricing for ESi1UM-10 1µm Epoxy Silicate Microspheres.

Brand: SHBC
Catalog Number: ESi1UM-10
Particle Size: 1µm
Solid Content: 5%
Surface Group: Epoxy
Manufacturer: Shanghai SanYu Biotechnology Co., Ltd.

For research and industrial raw material use only.