200um Polystyrene Microspheres PS200UM-10 5%

200µm Polystyrene Microspheres PS200UM-10

SHBC PS200UM-10 Polystyrene Microspheres are uniform 200µm polymer beads supplied as a 5% aqueous suspension.

The plain polystyrene surface supports physical adsorption of antibodies, antigens and other proteins. The large particle size allows convenient microscopic observation, filtration, sedimentation and bead recovery.

Product Overview

PS200UM-10 is designed for large-particle immunoassay research, protein adsorption studies and bead-based method development.

Unlike nanometer latex particles, 200µm microspheres are easy to observe and handle individually. They are suitable for applications requiring a visible, recoverable and mechanically stable polystyrene carrier.

Key Specifications

Key Product Advantages

• Uniform 200µm particle size

• Easy microscopic observation

• Plain hydrophobic polystyrene surface

• Suitable for passive protein adsorption

• Easy separation by sedimentation or filtration

• Convenient washing and bead recovery

• Stable spherical particle carrier

• Suitable for large-particle assay development

• Consistent batch manufacturing

• Bulk and customized supply available

Physical Adsorption of Proteins

Antibodies, antigens and other proteins can adsorb onto the plain polystyrene surface through hydrophobic, ionic and other non-covalent interactions.

Physical adsorption provides a simple coating method without EDC or NHS activation.

Important development parameters include:

• Protein concentration

• Buffer pH

• Ionic strength

• Coating time

• Mixing speed

• Blocking reagent

• Washing conditions

• Storage formulation

Coating efficiency and biological activity should be evaluated for each protein.

Immunoassay and Research Applications

PS200UM-10 can be evaluated for:

• Antibody adsorption studies

• Antigen immobilization

• Large-particle immunoassay carriers

• Bead-based binding assays

• Protein coating optimization

• Blocking reagent screening

• Non-specific adsorption studies

• Microscopy method development

• Particle counting and imaging

• Filtration and separation research

• Model particle experiments

• Biotechnology process validation

Why Choose 200µm Microspheres

The large 200µm particle size provides clear visibility under conventional microscopy and simplifies physical collection.

Compared with nanoscale particles, PS200UM-10 offers:

• Easier individual particle observation

• Faster gravitational sedimentation

• Simpler filtration and sieving

• Easier washing and recovery

• Lower risk of loss during routine handling

• A defined large-particle surface for coating studies

These particles are suitable when easy handling and visual analysis are more important than maximum surface area.

Handling and Application Considerations

Because 200µm microspheres settle faster than nanometer latex particles, the suspension should be gently mixed before sampling.

Continuous or intermittent mixing may be required during protein coating to maintain uniform particle contact.

Avoid aggressive mixing that may generate foam or damage adsorbed proteins. A wide-bore pipette tip is recommended when transferring the suspension.

PS200UM-10 is not intended as a direct replacement for nanoscale latex particles used in conventional immunoturbidimetric reagents.

Why Choose SHBC

Shanghai SanYu Biotechnology Co., Ltd. manufactures microsphere materials for immunoassay, biotechnology and life science research.

SHBC provides:

• Controlled particle manufacturing

• Reliable particle size consistency

• Stable batch-to-batch supply

• Laboratory and production quantities

• Flexible technical specifications

• OEM and private-label services

• Application-oriented technical support

Bulk Supply and Customization

PS200UM-10 is available for laboratory evaluation, pilot production and bulk manufacturing.

Customization options include:

• Particle diameter

• Particle size range

• Solids concentration

• Surface chemistry

• Buffer formulation

• Surfactant concentration

• Preservative system

• Packaging volume

• OEM labeling

Carboxyl, amino and other functionalized surfaces can also be developed for covalent biomolecule coupling.

Frequently Asked Questions

What is PS200UM-10?

PS200UM-10 is a 200µm plain polystyrene microsphere suspension supplied at 5% solids.

Can antibodies be adsorbed directly?

Yes. Antibodies and other proteins can be physically adsorbed onto the plain polystyrene surface.

Is chemical activation required?

No chemical activation is normally required for physical adsorption. Coating and blocking conditions must still be optimized.

What is the advantage of the 200µm size?

The large particles are easy to observe, filter, wash, recover and analyze individually.

Can PS200UM-10 be used for immunoturbidimetric assays?

It is not designed as a direct replacement for nanoscale latex particles commonly used in immunoturbidimetric reagents. It is better suited for large-particle binding assays and protein coating research.

Will the particles settle during storage or use?

Yes. Large 200µm particles may settle relatively quickly. Gently mix the suspension before sampling and during coating when necessary.

Can the particle surface be customized?

Yes. Plain, carboxyl, amino and other customized surface chemistries can be supplied according to project requirements.

Is bulk production available?

Yes. SHBC supports sample evaluation, pilot-scale production and bulk supply for research institutions and reagent manufacturers.

Research Use Only

PS200UM-10 Polystyrene Microspheres are intended for research use and reagent development only. They are not intended for direct clinical diagnosis or therapeutic use.