300nm Red Blood Cell Sorting Magnetic Beads
SHBC MCS300NM-10 Red Blood Cell Sorting Magnetic Beads are 300nm magnetic microspheres developed for immunomagnetic red blood cell separation reagent research and manufacturing.
With a 5% solids concentration, uniform particle size and customizable surface chemistry, these beads provide a reliable magnetic carrier for antibody or ligand immobilization in red blood cell depletion and erythroid cell enrichment workflows.
Product Overview
MCS300NM-10 magnetic beads are designed for the development of research-use red blood cell sorting reagents.
After conjugation with a suitable antibody or binding ligand, the beads can recognize red blood cells or erythroid cells and enable rapid magnetic separation from complex biological samples.
The 300nm particle size provides a practical balance between available binding surface, suspension stability and magnetic handling.
Key Specifications
Parameter | Specification |
|---|
Product Name | Red Blood Cell Sorting Magnetic Beads |
Catalog Number | MCS300NM-10 |
Particle Size | 300nm |
Solids Content | 5% |
Product Form | Magnetic bead suspension |
Main Use | Red blood cell separation reagent development |
Supply Type | Research and bulk manufacturing |
Brand | SHBC |
Manufacturer | Shanghai SanYu Biotechnology Co., Ltd. |
Key Advantages
Uniform 300nm particle size
Good suspension stability
High available surface area
Efficient magnetic separation
Suitable for antibody or ligand immobilization
Low non-specific adsorption design
Consistent batch-to-batch quality
Compatible with manual and automated workflows
Bulk supply for reagent manufacturers
OEM and surface customization available
Red Blood Cell Sorting Applications
MCS300NM-10 magnetic beads can be used to develop reagents for:
Red blood cell depletion
Erythroid cell enrichment
CD235a or Glycophorin A targeting systems
Whole blood sample preparation
Buffy coat processing
Umbilical cord blood research
Bone marrow sample processing
Leukocyte enrichment
Flow cytometry sample preparation
Cell culture and molecular analysis
Target-specific antibody or ligand conjugation is required according to the intended cell type, species and separation method.
How the Magnetic Separation Works
A red blood cell-specific antibody or ligand is immobilized on the magnetic bead surface.
The functionalized beads are then mixed with the biological sample. Target red blood cells bind to the magnetic beads through the selected surface marker.
When an external magnetic field is applied, bead-bound cells are retained while the unbound cell fraction can be collected.
The beads may be used for either red blood cell depletion or erythroid cell enrichment, depending on the assay design.
Why Choose 300nm Magnetic Beads
The 300nm particle size offers a large binding surface while maintaining good dispersion in aqueous buffers.
Compared with larger magnetic particles, nanoscale beads can provide more interaction sites with target cells. Compared with extremely small nanoparticles, 300nm beads are easier to collect using common magnetic separation equipment.
This makes MCS300NM-10 suitable for developing scalable immunomagnetic cell separation reagents.
Customization and Bulk Manufacturing
SHBC supports research institutes, diagnostic reagent developers and biotechnology manufacturers with scalable magnetic bead production.
Available customization services may include:
Surface functional group modification
Antibody or ligand conjugation
Particle size adjustment
Solids concentration adjustment
Buffer formulation
Magnetic response optimization
Custom packaging
OEM and private-label production
Production batches can be supplied with quality documentation according to project requirements.
Frequently Asked Questions
What is MCS300NM-10 used for?
MCS300NM-10 is used as a magnetic carrier for developing red blood cell depletion, erythroid cell enrichment and blood sample preparation reagents.
Are the beads supplied with an antibody?
The standard product is supplied as a magnetic bead raw material. Antibody or ligand conjugation can be developed according to the target marker and application.
Can the beads target CD235a or Glycophorin A?
The beads can be functionalized with suitable antibodies targeting CD235a, Glycophorin A or other red blood cell-associated markers.
Which samples can be processed?
Potential sample types include whole blood, buffy coat, cord blood, bone marrow and other red blood cell-containing samples. Each application requires protocol optimization.
Can the beads be used for negative selection?
Yes. After suitable functionalization, the beads can capture unwanted red blood cells so that the unbound nucleated cell fraction can be collected.
Are bulk quantities available?
Yes. SHBC supports laboratory evaluation, pilot production and bulk manufacturing for immunomagnetic reagent developers.
Is customization available?
Yes. Particle size, surface chemistry, concentration, buffer, packaging and biomolecule conjugation can be customized according to project requirements.
Research Use Only
MCS300NM-10 Red Blood Cell Sorting Magnetic Beads are intended for research use and reagent development only. They are not intended for direct clinical diagnosis or therapeutic use.
