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SHBC provides colored microspheres, fluorescent microspheres, magnetic beads, silica microspheres, chromatography packing microspheres and biological reagents for diagnostic assay development, nucleic acid extraction, protein purification and separation applications.

Home PMMA Microspheres PMMAC3UM-10 3μm Carboxyl PMMA Microspheres for Protein and Antibody Coupling

PMMAC3UM-10 3μm Carboxyl PMMA Microspheres for Protein and Antibody Coupling

PMMAC3UM-10 Carboxyl PMMA Microspheres are monodisperse polymethyl methacrylate microspheres functionalized with surface carboxyl (-COOH) groups. Supplied as a 5% aqueous suspension, they provide excellent stability and high coupling efficiency for proteins, antibodies, peptides and other biomolecules through EDC/NHS chemistry.

Cat.：
PMMAC3UM-10
Solid content：
5% Suspension
Diameter：
3 μm (Nominal Size: 3 μm)
Package：
10 mL / 20 mL / 100 mL

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Product Description

Product Overview

PMMAC3UM-10 Carboxyl PMMA Microspheres are uniform polymethyl methacrylate microspheres with surface carboxyl (-COOH) functional groups. The carboxyl groups enable efficient covalent coupling with proteins, antibodies, peptides, enzymes and other biomolecules using standard EDC/NHS activation chemistry.

Supplied as a 5% aqueous suspension, these microspheres exhibit excellent particle uniformity, low nonspecific adsorption and outstanding suspension stability. They are widely used in immunodiagnostics, biosensor development, lateral flow assays, molecular biology and life science research.

The highly uniform particle size and stable surface chemistry make PMMAC3UM-10 an excellent choice for assay development and functional biomolecule immobilization.

Key Features

Surface carboxyl (-COOH) functional groups
Excellent EDC/NHS coupling efficiency
High protein and antibody binding capacity
Uniform particle size distribution
Excellent suspension stability
Low nonspecific adsorption
Suitable for biomolecule immobilization
Compatible with immunoassays
5% aqueous suspension
Excellent batch-to-batch consistency

Technical Specifications

Parameter	Specification
Product Code	PMMAC3UM-10
Material	PMMA
Surface Functional Group	Carboxyl (-COOH)
Particle Size	3 μm
Solid Content	5% Suspension
Appearance	White Milky Suspension
Storage	2–8°C
Packaging	10 mL / 20 mL / 100 mL

Applications

Antibody immobilization
Protein conjugation
Peptide coupling
Enzyme immobilization
Lateral flow immunoassays
Latex agglutination assays
Immunodiagnostic reagent development
Molecular biology research
Biosensor development
Life science research

Product Advantages

PMMAC3UM-10 combines highly uniform PMMA microspheres with stable surface carboxyl functional groups, providing reliable covalent coupling through EDC/NHS chemistry. The microspheres offer high biomolecule loading efficiency, excellent suspension stability and low nonspecific binding, making them ideal for diagnostic assay development, immunoassays and biosensor applications.

Storage and Handling

Store at 2–8°C.
Do not freeze.
Keep the container tightly closed.
Avoid prolonged exposure to direct sunlight.
Gently invert or shake before use.
Do not centrifuge at excessive speed unless experimentally validated.

Customization Service

SANYU GROUP provides customized Carboxyl PMMA Microspheres including:

Customized particle sizes
Customized carboxyl density
Customized solid contents
Buffer optimization
OEM manufacturing
Bulk production
Custom packaging

Frequently Asked Questions

What are Carboxyl PMMA Microspheres?

Carboxyl PMMA Microspheres are PMMA microspheres functionalized with surface carboxyl (-COOH) groups for covalent attachment of proteins, antibodies and other biomolecules.

How are proteins coupled to PMMAC3UM-10?

Proteins and antibodies are typically coupled using EDC/NHS activation chemistry, which activates the carboxyl groups to form stable covalent amide bonds with primary amines.

What applications are PMMAC3UM-10 suitable for?

They are widely used in immunodiagnostics, lateral flow assays, latex agglutination tests, biosensors, molecular biology and biomedical research.

Can PMMAC3UM-10 be customized?

Yes. SANYU GROUP offers customization of particle size, carboxyl density, solid content, buffer system, packaging and OEM production.

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