Product Overview
SHBC Endotoxin TopAC 4FF is a Poly-L-Lysine affinity chromatography resin designed for bacterial endotoxin removal.
According to the supplied product information, the medium is prepared by covalently coupling Poly-L-Lysine to Top-4FF agarose gel. Poly-L-Lysine is a polymer of lysine that can specifically bind bacterial endotoxins under appropriate conditions, enabling endotoxin removal.
Endotoxin TopAC 4FF provides a specified dynamic binding capacity of 5000–10000 EU/mL and is suitable for endotoxin removal applications in the biopharmaceutical field.
Key Features
Poly-L-Lysine endotoxin removal resin
Poly-L-Lysine affinity ligand
Top-4FF agarose gel matrix
Dynamic binding capacity: 5000–10000 EU/mL
Specifically binds bacterial endotoxins under appropriate conditions
Designed for endotoxin removal
Safe and non-toxic medium
Suitable for biopharmaceutical applications
Package sizes from 25 mL to 20 L
Technical Specifications
Parameter | Specification |
|---|
Product Name | Endotoxin TopAC 4FF |
Brand | SHBC |
English Name | Poly-L-Lysine Endotoxin Removal Resin 4FF |
Series | 4FF |
Matrix | Top-4FF Agarose Gel |
Ligand | Poly-L-Lysine |
Dynamic Binding Capacity | 5000–10000 EU/mL |
Main Function | Bacterial Endotoxin Removal |
Product Type | Endotoxin Removal Affinity Resin |
Application | Biopharmaceutical Endotoxin Removal |
Package | 25 mL / 100 mL / 300 mL / 1 L / 5 L / 10 L / 20 L |
SHBC Art.No. | Packaging Specification |
|---|
A5141 | 25 mL |
A5142 | 100 mL |
A5143 | 300 mL |
A5144 | 1 L |
A5145 | 5 L |
A5146 | 10 L |
A5147 | 20 L |
Poly-L-Lysine Affinity Ligand
Endotoxin TopAC 4FF uses Poly-L-Lysine as its functional affinity ligand.
Poly-L-Lysine is described in the supplied product information as a polymer of lysine.
The product is prepared by covalently coupling Poly-L-Lysine to the Top-4FF agarose gel matrix, producing an affinity medium for bacterial endotoxin removal.
Bacterial Endotoxin Binding
Under appropriate conditions, Poly-L-Lysine can specifically bind bacterial endotoxins.
This interaction enables Endotoxin TopAC 4FF to capture endotoxins from suitable samples, providing an affinity-based approach to endotoxin removal.
Dynamic Binding Capacity
The specified dynamic binding capacity of Endotoxin TopAC 4FF is:
5000–10000 EU/mL
The unit provided in the supplied product table is EU/mL, reflecting its application in bacterial endotoxin removal.
Endotoxin Removal
Endotoxin TopAC 4FF is specifically designed for endotoxin removal.
The immobilized Poly-L-Lysine ligand interacts with bacterial endotoxins under appropriate conditions, allowing endotoxins to be captured by the affinity medium.
This makes the resin suitable for purification processes where reduction or removal of bacterial endotoxin is required.
Biopharmaceutical Applications
According to the supplied product information, Endotoxin TopAC 4FF is suitable for endotoxin removal in the biopharmaceutical field.
Its combination of an agarose gel matrix and immobilized Poly-L-Lysine ligand provides an affinity medium specifically intended for this application.
Safe and Non-Toxic Affinity Medium
The supplied product information describes the medium as safe and non-toxic.
This characteristic, together with its ability to bind bacterial endotoxins, supports its application in biopharmaceutical endotoxin removal processes.
Applications
SHBC Endotoxin TopAC 4FF can be used for:
Bacterial endotoxin removal
Endotoxin affinity purification
Biopharmaceutical endotoxin removal
Biopharmaceutical purification
Endotoxin capture
Downstream purification applications
Product Advantages
Endotoxin TopAC 4FF provides:
Poly-L-Lysine affinity ligand
Top-4FF agarose gel matrix
5000–10000 EU/mL dynamic binding capacity
Specific bacterial endotoxin binding under appropriate conditions
Designed specifically for endotoxin removal
Safe and non-toxic affinity medium
Suitable for biopharmaceutical applications
Seven package sizes from 25 mL to 20 L
Poly-L-Lysine for Endotoxin Removal
Poly-L-Lysine is a polymer of lysine that can specifically bind bacterial endotoxins under appropriate conditions.
Endotoxin TopAC 4FF immobilizes Poly-L-Lysine on a Top-4FF agarose gel matrix, allowing the ligand to be used as an affinity medium for endotoxin capture and removal.
This provides a chromatography-based option for endotoxin removal in suitable biopharmaceutical purification processes.
Endotoxin Removal Affinity Chromatography
Affinity-based endotoxin removal relies on interactions between the immobilized ligand and bacterial endotoxins.
For Endotoxin TopAC 4FF, Poly-L-Lysine serves as the affinity ligand.
The supplied product information specifies a dynamic binding capacity of 5000–10000 EU/mL, providing a quantitative reference for the endotoxin-binding performance of the medium.
Available Package Sizes
Endotoxin TopAC 4FF is available in:
25 mL / 100 mL / 300 mL / 1 L / 5 L / 10 L / 20 L
This package range supports different endotoxin removal and purification volumes.
Frequently Asked Questions
What is Endotoxin TopAC 4FF?
Endotoxin TopAC 4FF is a Poly-L-Lysine affinity resin designed for bacterial endotoxin removal.
What is the English product name?
The supplied English name is Poly-L-Lysine Endotoxin Removal Resin 4FF.
What ligand does Endotoxin TopAC 4FF use?
It uses Poly-L-Lysine as the affinity ligand.
What is Poly-L-Lysine?
According to the supplied product information, Poly-L-Lysine is a polymer of lysine.
What matrix is used?
The supplied information states that Poly-L-Lysine is covalently coupled to Top-4FF agarose gel.
What is the dynamic binding capacity?
The specified dynamic binding capacity is 5000–10000 EU/mL.
What does EU/mL refer to?
The supplied table uses EU/mL for the dynamic binding capacity of this endotoxin removal resin.
What is the main application?
The primary application is bacterial endotoxin removal.
How does Endotoxin TopAC 4FF remove endotoxins?
According to the supplied information, Poly-L-Lysine can specifically bind bacterial endotoxins under appropriate conditions, enabling endotoxin removal.
Is it suitable for biopharmaceutical applications?
Yes. The supplied information specifically states that the medium is suitable for endotoxin removal in the biopharmaceutical field.
Is the medium described as non-toxic?
Yes. The supplied information describes the medium as safe and non-toxic.
Is the particle size specified?
No. A numerical particle size is not provided in the supplied table.
Is the recommended flow rate specified?
No. The supplied information does not provide a numerical recommended flow rate.
Is pressure resistance specified?
No. A numerical pressure resistance value is not provided.
What package sizes are available?
Available sizes are 25 mL, 100 mL, 300 mL, 1 L, 5 L, 10 L and 20 L.
What are the SHBC Art.No. numbers?
The corresponding Art.No. are A5141–A5147.
What brand is Endotoxin TopAC 4FF?
Endotoxin TopAC 4FF is supplied under the SHBC brand.
