
Products
SHBC provides colored microspheres, fluorescent microspheres, magnetic beads, silica microspheres, chromatography packing microspheres and biological reagents for diagnostic assay development, nucleic acid extraction, protein purification and separation applications.
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RH1228
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250 g
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Guanidine Thiocyanate
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BioChemika Grade >99%
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Guanidine Thiocyanate
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593-84-0
Product Overview
RH1228 Guanidine Thiocyanate, CAS 593-84-0, is supplied as BioChemika Grade >99% for nucleic acid extraction, biochemical research, protein denaturation and laboratory sample preparation.
Guanidine Thiocyanate is a strong chaotropic and denaturing reagent widely used in molecular biology and biochemical research. It is particularly useful in sample preparation workflows involving nucleic acids and proteins.
RH1228 is supplied in a 250 g package.
Key Features
Guanidine Thiocyanate
CAS No. 593-84-0
BioChemika Grade >99%
Strong chaotropic reagent
Suitable for nucleic acid extraction
Suitable for RNA and DNA sample preparation
Suitable for protein denaturation
Suitable for biochemical research
250 g standard package
Technical Specifications
Parameter | Specification |
|---|---|
Product Code | RH1228 |
Product Name | Guanidine Thiocyanate |
CAS No. | 593-84-0 |
Grade | BioChemika Grade >99% |
Package | 250 g |
Applications
Nucleic Acid Extraction
RNA Extraction
DNA Extraction
Protein Denaturation
Molecular Biology Research
Biochemical Research
Biological Sample Preparation
Laboratory Reagent Preparation
Life Science Research
Guanidine Thiocyanate as a Denaturant
Guanidine Thiocyanate is commonly used as a strong denaturing and chaotropic reagent in biochemical and molecular biology research.
It can disrupt interactions responsible for maintaining the structure of proteins and other biological macromolecules.
RH1228 can therefore be used in compatible laboratory protocols requiring strong denaturing conditions.
Guanidine Thiocyanate for Nucleic Acid Extraction
One of the important laboratory applications of Guanidine Thiocyanate is nucleic acid sample preparation.
It can be incorporated into suitable extraction and lysis formulations used during isolation of nucleic acids from biological samples.
Potential applications include:
RNA extraction
DNA extraction
Sample lysis
Nucleic acid purification research
Molecular biology sample preparation
The complete extraction formulation should be prepared according to the specific experimental protocol.
Guanidine Thiocyanate for RNA Extraction
RNA sample preparation requires careful control of conditions that may affect RNA integrity.
Guanidine Thiocyanate is commonly incorporated into RNA extraction workflows because of its strong chaotropic and protein-denaturing properties.
RH1228 can be evaluated in suitable RNA isolation and molecular biology research protocols.
Guanidine Thiocyanate for DNA Extraction
RH1228 can also be evaluated in compatible DNA extraction and purification workflows.
The reagent may be incorporated into suitable lysis or sample preparation formulations depending on the extraction method being used.
Compatibility with downstream purification and analytical procedures should be considered.
Guanidine Thiocyanate for Protein Denaturation
Guanidine Thiocyanate provides strong denaturing conditions and can be used in suitable protein-related biochemical research.
Potential applications include:
Protein denaturation
Biological sample lysis
Protein structure disruption
Biochemical sample preparation
Biomolecule research
The appropriate concentration depends on the specific experimental protocol.
Guanidine Thiocyanate for Molecular Biology Research
RH1228 can be used in molecular biology workflows involving biological sample preparation and nucleic acid research.
Potential research applications include:
RNA isolation
DNA isolation
Cell and tissue sample preparation
Molecular biology reagent formulation
Nucleic acid purification research
Biochemical analysis
Guanidine Thiocyanate as a Chaotropic Agent
Guanidine Thiocyanate is classified as a chaotropic agent.
Chaotropic reagents can disrupt non-covalent interactions within biological macromolecules and are therefore useful in applications requiring denaturation or disruption of biological structures.
Its strong chaotropic properties make it useful in many biochemical and molecular biology sample preparation workflows.
Guanidine Thiocyanate vs Guanidine Hydrochloride
Guanidine Thiocyanate and Guanidine Hydrochloride are different guanidinium-based reagents.
Both can provide denaturing conditions, but their properties and common applications differ.
Guanidine Thiocyanate is particularly associated with nucleic acid extraction and molecular biology sample preparation, while Guanidine Hydrochloride is widely used in protein denaturation and protein folding research.
Selection should be based on the specific experimental protocol.
Guanidine Thiocyanate vs Urea
Guanidine Thiocyanate and urea can both be used in applications requiring disruption of biomolecular interactions, but they have different chemical properties.
The appropriate reagent depends on:
Target biomolecule
Required denaturing conditions
Sample type
Extraction method
Downstream analysis
Experimental protocol
They should not automatically be substituted for one another.
BioChemika Grade >99% Guanidine Thiocyanate
RH1228 is specified in the supplied product table as:
BioChemika Grade >99%
This specification is suitable for biochemical, molecular biology and life science research applications requiring this grade of Guanidine Thiocyanate.
How to Select Guanidine Thiocyanate for Research
When using Guanidine Thiocyanate, researchers should consider:
Target biomolecule
RNA or DNA extraction method
Sample type
Required denaturing conditions
Working concentration
Buffer formulation
Downstream purification method
Analytical technique
The appropriate conditions should be selected according to the specific experimental protocol.
Product Advantages
RH1228 provides Guanidine Thiocyanate, CAS 593-84-0, BioChemika Grade >99% for biochemical and molecular biology research.
It can be used in compatible nucleic acid extraction, RNA and DNA sample preparation, protein denaturation and other life science research workflows.
The standard package is 250 g.
Storage and Handling
Keep the container tightly sealed.
Protect from moisture and contamination.
Use appropriate laboratory protective equipment.
Use clean laboratory equipment during handling.
Prepare solutions according to experimental requirements.
Avoid contamination of the bulk product.
Store according to applicable product documentation.
Packaging
Standard Package: 250 g
Bulk quantity requirements can be discussed upon request.
Frequently Asked Questions (FAQ)
What is RH1228?
RH1228 is Guanidine Thiocyanate, supplied as BioChemika Grade >99%.
What is the CAS number of RH1228 Guanidine Thiocyanate?
The CAS number is 593-84-0.
What grade is RH1228?
RH1228 is specified as BioChemika Grade >99%.
What is Guanidine Thiocyanate used for?
It is commonly used for nucleic acid extraction, RNA and DNA sample preparation, protein denaturation and biochemical research.
Is Guanidine Thiocyanate a denaturant?
Yes. Guanidine Thiocyanate is a strong chaotropic and denaturing reagent.
Can Guanidine Thiocyanate be used for RNA extraction?
Yes. It is commonly used in compatible RNA extraction and molecular biology sample preparation workflows.
Can Guanidine Thiocyanate be used for DNA extraction?
Yes. It can be evaluated in suitable DNA extraction and purification workflows.
Is Guanidine Thiocyanate the same as Guanidine Hydrochloride?
No. They are different guanidinium-based reagents with different properties and common applications.
What concentration of Guanidine Thiocyanate should be used?
The supplied product table does not specify a universal working concentration. The appropriate concentration should follow the specific extraction or experimental protocol.
What packaging is available?
RH1228 Guanidine Thiocyanate is supplied in a 250 g package.


